Thanks again to The New Yorker, this time for responding to that timeless cry of humanity -- "OH PLEASE MAKE IT STOP!" -- with Joan Acocella's study of the human hangover.
A taste:
As for hangover remedies, they are legion. There are certain unifying themes, however. When you ask people, worldwide, how to deal with a hangover, their first answer is usually the hair of the dog. The old faithful in this category is the Bloody Mary, but books on curing hangovers—I have read three, and that does not exhaust the list—describe more elaborate potions, often said to have been invented in places like Cap d’Antibes by bartenders with names like Jean-Marc. An English manual, Andrew Irving’s “How to Cure a Hangover” (2004), devotes almost a hundred pages to hair-of-the-dog recipes, including the Suffering Bastard (gin, brandy, lime juice, bitters, and ginger ale); the Corpse Reviver (Pernod, champagne, and lemon juice); and the Thomas Abercrombie (two Alka-Seltzers dropped into a double shot of tequila). Kingsley Amis suggests taking Underberg bitters, a highly alcoholic digestive: “The resulting mild convulsions and cries of shock are well worth witnessing. But thereafter a comforting glow supervenes.” Many people, however, simply drink some more of what they had the night before. My Ukrainian informant described his morning-after protocol for a vodka hangover as follows: “two shots of vodka, then a cigarette, then another shot of vodka.” A Japanese source suggested wearing a sake-soaked surgical mask.
Application of the hair of the dog may sound like nothing more than a way of getting yourself drunk enough so that you don’t notice you have a hangover, but, according to Wayne Jones, of the Swedish National Laboratory of Forensic Medicine, the biochemistry is probably more complicated than that. Jones’s theory is that the liver, in processing alcohol, first addresses itself to ethanol, which is the alcohol proper, and then moves on to methanol, a secondary ingredient of many wines and spirits. Because methanol breaks down into formic acid, which is highly toxic, it is during this second stage that the hangover is most crushing. If at that point you pour in more alcohol, the body will switch back to ethanol processing. This will not eliminate the hangover—the methanol (indeed, more of it now) is still waiting for you round the bend—but it delays the worst symptoms. It may also mitigate them somewhat. On the other hand, you are drunk again, which may create difficulty about going to work.
